[She shows him a rare, soft smile. While the kizuna side effects are partly responsible, she's also touched by Itto's concern.]

Thanks, Itto. Same to you. Let me know if anyone's being an asshole to you. I'm tougher than I look.

[Given what he saw with Nyuu, those vectors are certainly deadly.

In another (what may be considered) surprising move, the kizuna side effects compel Lucy to offer her hand to Itto. She's not usually the one to initiate physical contact - unless her inhibitions have been lowered like in the present moment. But she also trusts Itto. Her smile widens and becomes more warm.]

You're a good friend.