They're probably not. Outside of vampires, though, mostly we just have some wild animals and other humans causing trouble, so I guess it's a matter of ratio.

[maybe the most odd thing, actually, is the way that word cracks Vael's entire veneer. destiny. he doesn't repeat it aloud, but the way it sours his expression is painfully clear, no matter how quickly he wipes it away. and, for all his comfort otherwise, there's a thick undertone of.... disappointment? frustration? or... it might be closest to hatred, when he speaks in turn.]

No, I don't think destiny does much of anything, for us. Higher powers, faith, destiny... better you just fight tooth and nail for whatever you have than put trust in anything else.